Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 18382576 | HCID 18382576 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 18382648 | HCID 18382648 | — |
Reaction Steps
7-Nitro-3,3-dimethyl-3,4-dihydroisoquinoline (1.0 g, 4.9 mmol) in acetone (100 ml) was treated with iodomethane (1 ml, 16 mmol). The mixture was stirred at 25° C. for 18 h and the resultant precipitate collected by filtration and dried; pale yellow powder (1.5 g, 88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06492378B1 |
|---|
| Source dataset | uspto-grants-2002_12 |
|---|
| ORD ID | ord-ad5a959a6a9b49f094c171b59f0befc5 |
|---|
| Source note | uspto-grants-2002_12 |
|---|
