HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butylamine → HCID 86588189, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | HCID 18336823 | HCID 18336823 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86588189 | HCID 86588189 | 77.3% |
Reaction Steps
To (2R,3R,4R,5S)-4-(acetyloxy)-5-{3-[(acetyloxy)methyl]isoxazol-5-yl}-2-[2-chloro-6-(4-chloro-2-fluoroanilino)-9H-purin-9-yl]tetrahydrofuran-3-yl acetate (4.02 mg) in methanol (2 ml) at 0° C. was added tert-butylamine (0.012 ml), and the mixture was allowed to stand at 0 ° C. for 3 h. The solvent was evaporated in vacuo to furnish the title compound as a yellow gum (2.48 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492348B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-91b0f30812b649cbab5b97f195b84673 |
| Source note | uspto-grants-2002_12 |