反应详情

(1S)-1-Benzyl-2-(benzyloxy)-N-(t-butoxycarbonyl)ethylamine (205 mg) is dissolved in a 2.3 N solution of hydrogen chloride in methanol (3 ml), and the solution is stirred for one hour. The reaction mixture is concentrated under reduced pressure, ether is added to the concentrate, and the resulting precipitate is filtered off to give 143 mg (99%) of the titled compound (Reference compound No. 12-1) as crystals.

1. concentrationThe reaction mixture is concentrated under reduced pressure, ether
2. additionis added to the concentrate
3. filtrationthe resulting precipitate is filtered off