Benzyl Bromide → 3-benzylsulfanyl-5-furan-2-yl-4-(4-methoxy-benzyl)-4H-1,2,4-triazole

HRID 229772Notes

Reaction equation

HRID 229772 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([NH:8][NH2:9])=O.[CH3:10][O:11][C:12]1[CH:21]=[CH:20][C:15]([CH2:16][N:17]=[C:18]=[S:19])=[CH:14][CH:13]=1.[CH2:22](Br)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:22]([S:19][C:18]1[N:17]([CH2:16][C:15]2[CH:20]=[CH:21][C:12]([O:11][CH3:10])=[CH:13][CH:14]=2)[C:6]([C:2]2[O:1][CH:5]=[CH:4][CH:3]=2)=[N:8][N:9]=1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

4

Reactant 3

HCID 7498Benzyl BromideHCID 187312-Furancarboxylic acid, hydrazideHCID 123197Benzene, 1-(isothiocyanatomethyl)-4-methoxy-

Product 1

HCID 113723403-benzylsulfanyl-5-furan-2-yl-4-(4-methoxy-benzyl)-4H-1,2,4-triazole

Procedure

This compound was synthesized using the same methodology as described in Example 1 above, using 2-furancarboxylic acid hydrazide, 4-methoxybenzyl isothiocyanate and benzyl bromide as the starting materials.

Workup

  1. customThis compound was synthesized

Sources & evidence

ORD record
ord-dd2ed4f854ff42fcae6e2f8e31ce5885
Source dataset
uspto-grants-2009_07
Patent number
US07563905B2

Reaction notes

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