Aminoethylpiperazine → HCID 18382942, compound

HRID 2297771Notes

Reaction equation

HRID 2297771 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH2:5]1.[NH:10]1[C:18]2[C:13](=[CH:14][C:15]([NH:19][C:20]3[C:21]4[S:28][C:27]([C:29]5[CH:36]=[CH:35][C:32]([CH:33]=O)=[CH:31][CH:30]=5)=[CH:26][C:22]=4[N:23]=[CH:24][N:25]=3)=[CH:16][CH:17]=2)[CH:12]=[CH:11]1>>[NH:10]1[C:18]2[C:13](=[CH:14][C:15]([NH:19][C:20]3[C:21]4[S:28][C:27]([C:29]5[CH:36]=[CH:35][C:32]([CH2:33][NH:1][CH2:2][CH2:3][N:4]6[CH2:9][CH2:8][NH:7][CH2:6][CH2:5]6)=[CH:31][CH:30]=5)=[CH:26][C:22]=4[N:23]=[CH:24][N:25]=3)=[CH:16][CH:17]=2)[CH:12]=[CH:11]1

Participants

3

Reactant 2

HCID 8795AminoethylpiperazineHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 18382942HCID 18382942, compound

Procedure

The title compound was prepared from N-(2-aminoethyl)-piperazine and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by the procedure analogous to example 17. M.P. 178-191° C.; LC-MS: 484 (MH+); HPLC RT: 3.41 minutes.

Sources & evidence

ORD record
ord-672284d309eb4822b82ad8c17f54d649
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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