HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (1H-Indol-5-yl)-[6-(4-methylaminomethyl-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 4-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde | HCID 18382759 | — |
| Product | (1H-Indol-5-yl)-[6-(4-methylaminomethyl-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-amine | HCID 18382985 | — |
Reaction Steps
The title compound was prepared from methylamine and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. The product was converted to the mesylate salt analogous to example 17 being converted to the HCl salt. M.P. 140-147° C.; LC-MS: 386 (MH−); HPLC RT: 3.54 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492383B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-6d69ce6f5bfa4750a8f480b9b61f6296 |
| Source note | uspto-grants-2002_12 |