Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297776Generated: October 30, 2026

Hydrochloric Acid → HCID 18382988, compound

https://huagongshe.com/reaction/2297776

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant3-Amino-1-propanolHCID 9086—
Reactant4-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehydeHCID 18382759—
ProductHCID 18382988HCID 18382988—

Reaction Steps

The title compound was prepared from 3-aminopropanol and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. The product was converted to the mesylate salt analogous to example 17 being converted to the HCl salt. 1H NMR (400 MHz, DMSO) d 11.1 (s, 1H), 9.54 (s, 1H), 8.44 (s, 1), 7.75 (dd, 4H), 7.42 (m, 4H), 7.23 (m, 1H), 6.41 (s, 1H), 3.67 (s, 2H), 3.43 (s, 2H), 3.30 (s, 2H), 1.54 (m, 2H); LC-MS: 430 (MH+); HPLC RT: 3.34 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06492383B1
Source datasetuspto-grants-2002_12
ORD IDord-9a68042896d740a785d5ef1061f5dc3c
Source noteuspto-grants-2002_12