反应详情

The product of Example 2 (2.0 g) and 10% Pd/C (350 mg) in DMF (20 mL) were shaken at 55 psi hydrogen for 3 hours. The catalyst was removed by filtration and the filtrate was concentrated under vacuum to yield a yellow wax. The wax was triturated with methanol and the resulting amber solid was collected by filtration to afford the title compound (1.6 g).

1. customThe catalyst was removed by filtration
2. concentrationthe filtrate was concentrated under vacuum
3. customto yield a yellow wax
4. customThe wax was triturated with methanol
5. filtrationthe resulting amber solid was collected by filtration