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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297805Generated: October 31, 2026

Aminoethylpiperazine → (1H-Indol-5-yl)-(2-{4-[(2-piperazin-1-yl-ethylamino)-methyl]-phenyl}-thieno[3,2-b]pyridine-7-yl)-amine

https://huagongshe.com/reaction/2297805

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAminoethylpiperazineHCID 8795—
Reactant4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzaldehydeHCID 18382743—
Product(1H-Indol-5-yl)-(2-{4-[(2-piperazin-1-yl-ethylamino)-methyl]-phenyl}-thieno[3,2-b]pyridine-7-yl)-amineHCID 18382875—

Reaction Steps

The title compound was prepared from 2-piperazin-1-yl-ethylamine and 4-[7-(1H-indol-5-ylamino)-thieno(3,2-b]pyridin-2-yl]-benzaldehyde by a procedure analogous to example 17. LC-MS: 483 (MH+); HPLC RT: 3.41 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06492383B1
Source datasetuspto-grants-2002_12
ORD IDord-e005a29f9be44d8fa6eec657cb8115f3
Source noteuspto-grants-2002_12