Phenylboronic Acid → HCID 18383089, compound

HRID 2297850Notes

Reaction equation

HRID 2297850 reaction equation
[C:1]1(B(O)O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[C:11]1[S:19][C:18]2[C:13](=[N:14][CH:15]=[CH:16][C:17]=2[NH:20][C:21]2[CH:22]=[C:23]3[C:27](=[CH:28][CH:29]=2)[NH:26][C:25]([CH3:30])=[CH:24]3)[CH:12]=1>>[CH3:30][C:25]1[NH:26][C:27]2[C:23]([CH:24]=1)=[CH:22][C:21]([NH:20][C:17]1[CH:16]=[CH:15][N:14]=[C:13]3[CH:12]=[C:11]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[S:19][C:18]=13)=[CH:29][CH:28]=2

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 183828502-Bromo-N-(2-methyl-1H-indol-5-yl)thieno[3,2-b]pyridin-7-amine

Product 1

HCID 18383089HCID 18383089, compound

Procedure

The title compound was prepared from phenyl boronic acid and (2-bromothieno[3,2-b]pyridin-7-yl)-(2-methyl-1H-indol-5-yl)-amine by the procedure analogous to example 2 above. 1H NMR (400 MHz, CD3OD) δ8.02 (d, 1H), 7.67 (d, 2H), 7.54 (s, 1H), 7.30 (m, 5H), 6.94 (d, 1H), 6.54 (d, 1H), 6.09 (s, 1H), 2.39 (s, 3H); RP18-HPLC RT: 6.21 minutes; API MS 356 (M+1).

Sources & evidence

ORD record
ord-46e6aba4f44245649027a27cde16f9a9
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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