Hydrochloric Acid → HCID 9845234, compound

Participants

Reaction Steps

Prepared as described in example 5d) above using (+/−)-[1-[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-3-pyrrolidinyl]-carbamic acid, 1,1-dimethylethyl ester (Example 7c), hydrochloric acid (0.5 ml of a 4N solution in dioxane) and methanol (5 ml). Evaporation under reduced pressure gave a solid on trirtuation with diethyl ether. Recrystallisation from methanol/diethyl ether gave the title compound as a solid (0.030 g).

Provenance & Evidence