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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2298109Generated: October 31, 2026

1,4,5,6-Tetrahydropyrimidine → 2-Chloro-5-[(5,6-dihydro-1(4H)-pyrimidinyl)methyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide

https://huagongshe.com/reaction/2298109

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4,5,6-TetrahydropyrimidineHCID 137105—
Reactant5-Bromomethyl-2chloro-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamideHCID 21900020—
Product2-Chloro-5-[(5,6-dihydro-1(4H)-pyrimidinyl)methyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamideHCID 18381567—

Reaction Steps

Prepared according to the method described in Example 8 from 5-bromomethyl-2-chloro-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide (Example 8b,) and 1,4,5,6-tetrahydro-pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06492355B1
Source datasetuspto-grants-2002_12
ORD IDord-fa75086b4fad47a2b337f9f232b0d628
Source noteuspto-grants-2002_12