Methanesulfonyl chloride → HCID 22246767, compound

HRID 2298174Notes

Reaction equation

HRID 2298174 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([Cl:12])[CH:11]=1)[O:5][CH2:6][CH2:7][NH2:8].[CH3:13][S:14](Cl)(=[O:16])=[O:15]>CCN(CC)CC>[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([Cl:12])[CH:11]=1)[O:5][CH2:6][CH2:7][NH:8][S:14]([CH3:13])(=[O:16])=[O:15]

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 499912-(3,5-Dichlorophenoxy)ethylamine

Product 1

HCID 22246767HCID 22246767, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound was prepared from 2-(3,5-dichloro-phenoxy)-ethylamine, Et3N, and methanesulfonyl chloride using the procedure described in Step 2 of Preparation A1. Recrystallization from EtOH provided the title compound. 1HNMR (400 MHz, CDCl3) δ 6.93 (m, 1H), 6.74 (m, 2H), 5.09 (m, 1H), 4.01 (t, 2H), 3.47 (q, 2H), 2.96 (s, 3H).

Workup

  1. customRecrystallization from EtOH

Sources & evidence

ORD record
ord-b81a64b2f63d44b89087ac679b64ba79
Source dataset
uspto-grants-2002_12
Patent number
US06492412B2

Reaction notes

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