HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetate → HCID 15389278, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetate | HCID 175 | — |
| Reactant | HCID 5307014 | HCID 5307014 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 15389278 | HCID 15389278 | — |
Reaction Steps
A solution of diethyl (4-pyridylmethylene)malonate [XXVIIIb] (97.6 g) in absolute ethanol (1 L) was hydrogenated in the presence of acetic acid glacial (35.5 g) and 10% Palladium on activated carbon catalyst (9.7 g) at 60° C. and 200 psi for 20 hours. The catalyst was filtered off and the resulting solution of the title compound in the form of acetic acid salt was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492522B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-44b5694bb4a24c35ba698b3e00e2f5e6 |
| Source note | uspto-grants-2002_12 |