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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2298585Generated: October 30, 2026

2-Bromo-1-(3,5-dimethoxyphenyl)ethanone → HCID 86758665, compound

https://huagongshe.com/reaction/2298585

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-(3,5-dimethoxyphenyl)ethanoneHCID 2756932—
ReactantMethyl 4-(aminothioxomethyl)-5-methylthiothiophene-2-carboxylateHCID 86583815—
ProductHCID 86758665HCID 8675866527.8%

Reaction Steps

100 mg (0.404 mmol) of methyl 4-(aminothioxomethyl)-5-methylthiothiophene-2-carboxylate (Maybridge Chemical Co. LTD., Cornwall, U.K.) was reacted with 2-bromo-3′,5′-dimethoxy acetophenone (0.444 mmol) in a manner similar to Example 22, step (a) to afford 44 mg (27% yield) of methyl 4-[4-(3,5-dimethoxyphenyl)(1,3-thiazol-2-yl)]-5-methylthiothiophene-2-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06492403B1
Source datasetuspto-grants-2002_12
ORD IDord-9cb06de0be104090924ed9c0a9a843a0
Source noteuspto-grants-2002_12