Mci-186 → Sodium 2-(3-methyl-5-oxo-1-phenyl-1,5-dihydropyrazol-4-ylidenemethyl)benzenesulfonate

HRID 2298699Notes

Reaction equation

HRID 2298699 reaction equation
[CH:1]1[CH:6]=[C:5]([CH:7]=O)[C:4]([S:9]([O-:12])(=[O:11])=[O:10])=[CH:3][CH:2]=1.[Na+:13].[CH3:14][C:15]1[CH2:19][C:18](=[O:20])[N:17]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[N:16]=1.C(N(CC)CC)C>C(O)C>[CH3:14][C:15]1[C:19](=[CH:7][C:5]2[CH:6]=[CH:1][CH:2]=[CH:3][C:4]=2[S:9]([O-:12])(=[O:11])=[O:10])[C:18](=[O:20])[N:17]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[N:16]=1.[Na+:13]

Participants

5

Reactant 3

HCID 4021Mci-186HCID 8471TriethylamineHCID 3794540Sodium o-formylbenzenesulfonate

Product 1

HCID 74088227Sodium 2-(3-methyl-5-oxo-1-phenyl-1,5-dihydropyrazol-4-ylidenemethyl)benzenesulfonate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.1 g of sodium benzaldehyde-2-sulfonate, 1.75 g of 3-methyl-1-phenyl-2-pyrazolin-5-one and 1 g of triethylamine in 20 mL of ethanol were allowed to reflux 5 hours. After cooling to room temperature, the precipitate was filtered off and dried.

Workup

  1. temperatureto reflux 5 hours
  2. filtrationthe precipitate was filtered off
  3. customdried

Sources & evidence

ORD record
ord-0abd5b8f110d4ed39d84f7c2da75aba5
Source dataset
uspto-grants-2002_12
Patent number
US06494923B2

Reaction notes

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