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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2298758Generated: October 31, 2026

Sodium Hydroxide → 4-(2-Methoxy-6H-pyrido[2',3':4,5]pyrrolo[2,1-a]isoindol-11-yl)-butanoic acid

https://huagongshe.com/reaction/2298758

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 4-(2-methoxy-6H-pyrido[2',3':4,5]pyrrolo[2,1-a]isoindol-11-yl)-3-butenoateHCID 69419312—
SolventEthanolHCID 702—
Product4-(2-Methoxy-6H-pyrido[2',3':4,5]pyrrolo[2,1-a]isoindol-11-yl)-butanoic acidHCID 18758207—

Reaction Steps

The ester obtained in Step A is placed in 150 ml of ethanol in the presence of 40 ml of 2N sodium hydroxide solution. The title acid is isolated after stirring at room temperature and then refluxing.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06495543B1
Source datasetuspto-grants-2002_12
ORD IDord-8baf6058e05444179f6f6d038d2ec189
Source noteuspto-grants-2002_12