1,3-Dibromopropane → HCID 18758223, compound

HRID 2298769Notes

Reaction equation

HRID 2298769 reaction equation
COC1[N:8]=[C:7]2C=CN[C:6]2=CC=1.[CH:12]([C:15]1[N:20]=[C:19]2[CH:21]=[CH:22][NH:23][C:18]2=[CH:17][CH:16]=1)([CH3:14])[CH3:13].Br[CH2:25][CH2:26][CH2:27]CBr.BrCCCBr>>[CH:12]([C:15]1[CH:16]=[CH:17][C:18]2[N:23]3[C:22]([CH2:25][CH2:26][CH2:27]3)=[C:21]([CH2:6][CH2:7][NH2:8])[C:19]=2[N:20]=1)([CH3:14])[CH3:13]

Participants

5

Reactant 4

HCID 80011,3-DibromopropaneHCID 80561,4-DibromobutaneHCID 53243695-methoxy-1H-pyrrolo[3,2-b]pyridineHCID 18758247HCID 18758247, compound

Product 1

HCID 18758223HCID 18758223, compound

Procedure

The procedure is as for Preparation 8, in Step A replacing 5-methoxy-1H-pyrrolo[3,2-b]pyridine by 5-isopropyl-1H-pyrrolo[3,2-b]pyridine and 1,4-dibromobutane by 1,3-dibromopropane.

Sources & evidence

ORD record
ord-7bd1c513c77f49b9861462ca532355da
Source dataset
uspto-grants-2002_12
Patent number
US06495543B1

Reaction notes

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