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HRID2298875

反应详情

EQUATION

反应方程式

HRID 2298875 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：COc1ccc(CNc2nc(CCC(=O)O)nc3sc4ccccc4c23)cc1Cl
HCID9910420

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(CNc2nc(CCC(=O)Cl)nc3sc4ccccc4c23)cc1Cl
HCID15895805

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

1 equivalent of 3-[4-(3-chloro-4-methoxybenzylamino)benzothieno[2,3-d]pyrimidin-2-yl]propionic acid and 1.2 equivalents of thionyl chloride are stirred in dichloromethane for 2 hours. The solvent is removed, affording 3-[4-(3-chloro-4-methoxybenzylamino)benzothieno[2,3-d]pyrimidin-2-yl]propionyl chloride.

WORKUP

后处理

  1. customThe solvent is removed