p-Toluenesulfonic acid → HCID 18379685, compound

HRID 2299047Notes

Reaction equation

HRID 2299047 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([NH2:7])=[O:6].[CH3:11][C:12]([CH:15]=O)([CH3:14])[CH3:13].[NH:17]1[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[N:19]=[N:18]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:17]1([CH:15]([NH:7][C:5](=[O:6])[C:4]2[CH:8]=[CH:9][CH:10]=[C:2]([F:1])[CH:3]=2)[C:12]([CH3:13])([CH3:14])[CH3:11])[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[N:19]=[N:18]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 12417PivalaldehydeHCID 680003-FluorobenzamideHCID 178418385HCID 178418385, compound

Product 1

HCID 18379685HCID 18379685, compound

Procedure

A suspension of 3-fluorobenzamide, pivaldehyde, benzotriazole, and p-toluenesulfonic acid was processed as described in Example 1C to provide the title compound.

Sources & evidence

ORD record
ord-9f011af820d04a0bbf5c37886229aa0f
Source dataset
uspto-grants-2002_12
Patent number
US06495576B2

Reaction notes

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