p-Toluenesulfonic acid → N-(1-(1H-1,2,3-Benzotriazol-1-yl)-2,2-dimethylpropyl)-3,5-dimethoxybenzamide

HRID 2299050Notes

Reaction equation

HRID 2299050 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([O:12][CH3:13])[CH:11]=1)[C:6]([NH2:8])=[O:7].[CH3:14][C:15]([CH:18]=O)([CH3:17])[CH3:16].[NH:20]1[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[N:22]=[N:21]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:20]1([CH:18]([NH:8][C:6](=[O:7])[C:5]2[CH:9]=[C:10]([O:12][CH3:13])[CH:11]=[C:3]([O:2][CH3:1])[CH:4]=2)[C:15]([CH3:16])([CH3:17])[CH3:14])[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[N:22]=[N:21]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 12417PivalaldehydeHCID 728783,5-DimethoxybenzamideHCID 178418385HCID 178418385, compound

Product 1

HCID 18379723N-(1-(1H-1,2,3-Benzotriazol-1-yl)-2,2-dimethylpropyl)-3,5-dimethoxybenzamide

Procedure

A suspension of 3,5-dimethoxybenzamide, pivaldehyde, benzotriazole, and p-toluenesulfonic acid was processed as described in Example 1C to provide the title compound.

Sources & evidence

ORD record
ord-bc3ac727aeb64854b40e2e4a2e4af16f
Source dataset
uspto-grants-2002_12
Patent number
US06495576B2

Reaction notes

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