HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl squarate → 3-(5-Bromo-6-fluoro-pyridin-3-ylamino)-4-ethoxy-cyclobut-3-ene-1,2-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl squarate | HCID 123228 | — |
| Reactant | 5-Bromo-6-fluoropyridin-3-amine | HCID 18379725 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(5-Bromo-6-fluoro-pyridin-3-ylamino)-4-ethoxy-cyclobut-3-ene-1,2-dione | HCID 18379698 | — |
Reaction Steps
A solution of 2-fluoro-3-bromo-5-aminopyridine and 3,4-diethoxy-3-cyclobutene-1,2-dione in ethanol was processed as described in Example 1A to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495576B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-930ace022d424c21977e644259830317 |
| Source note | uspto-grants-2002_12 |