p-Toluenesulfonic acid → HCID 18379688, compound

HRID 2299070Notes

Reaction equation

HRID 2299070 reaction equation
[C:1]1([CH2:7][CH2:8][C:9]([NH2:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:12][C:13]([CH:16]=O)([CH3:15])[CH3:14].[NH:18]1[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=2[N:20]=[N:19]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:18]1([CH:16]([NH:11][C:9](=[O:10])[CH2:8][CH2:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[C:13]([CH3:14])([CH3:15])[CH3:12])[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=2[N:20]=[N:19]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 76253-PhenylpropanamideHCID 12417PivalaldehydeHCID 178418385HCID 178418385, compound

Product 1

HCID 18379688HCID 18379688, compound

Procedure

A suspension of 3-phenyl-propionamide, pivaldehyde, benzotriazole, and p-toluenesulfonic acid was processed as described in Example 1C to provide the title compound.

Sources & evidence

ORD record
ord-8232644f1f8847e2a1e65b2c8077d852
Source dataset
uspto-grants-2002_12
Patent number
US06495576B2

Reaction notes

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