p-Toluenesulfonic acid → HCID 18379684, compound

HRID 2299072Notes

Reaction equation

[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([NH2:9])=[O:8].[CH3:10][C:11]([CH:14]=O)([CH3:13])[CH3:12].[NH:16]1[C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=2[N:18]=[N:17]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:16]1([CH:14]([NH:9][C:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)=[O:8])[C:11]([CH3:12])([CH3:13])[CH3:10])[C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=2[N:18]=[N:17]1

Participants

Reactant 4

HCID 6101p-Toluenesulfonic acid

HCID 12417Pivalaldehyde

HCID 150702-Pyridinecarboxamide

HCID 178418385HCID 178418385, compound

Product 1

HCID 18379684HCID 18379684, compound

Procedure

A suspension of 2-pyridinecarboxamide, pivaldehyde, benzotriazole, and p-toluenesulfonic acid was processed as described in Example 1C to provide the desired product.

Sources & evidence

ORD record: ord-88337db2fdfc4ac89d88887327a1354b
Source dataset: uspto-grants-2002_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06495576B2

Reaction notes

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