HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-Chloro-N-{1-[(3,4-dioxo-2-{[5-(trifluoromethyl)pyridin-3-yl]amino}-1-cyclobuten-1-yl)amino]-2,2-dimethyl-3-phenylpropyl}benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Amino4-(5-trifluoromethyl-3-pyridinylamino)cyclobut-3-ene-1,2-dione | HCID 18379677 | — |
| Reactant | N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dimethyl-3-phenylpropyl]-4-chlorobenzamide | HCID 18770575 | — |
| Product | 4-Chloro-N-{1-[(3,4-dioxo-2-{[5-(trifluoromethyl)pyridin-3-yl]amino}-1-cyclobuten-1-yl)amino]-2,2-dimethyl-3-phenylpropyl}benzamide | HCID 10144185 | — |
Reaction Steps
A suspension of the product from Example 52C, the product from Example 18B, and K2CO3 was processed as described in Example 1D to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495576B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-7ae9c7f8b0f34f11beca5cbac5950a7c |
| Source note | uspto-grants-2002_12 |