反应详情

To a solution of 3-cyclohexylmethyl-5-aminobenzimidazole (2.0 g, 8.7 mmol) in 40 ml of AcOH was added solution of Br2 in AcOH until it produces a precipitation. The reaction mixture was concentrated in vacuo to provide a brown solid which was subjected to column chromatography (5% NH3 sat'd MeOH/CHCl3) to provide 1.2 g (3.8 mmol, 48%) of the product.

1. customproduces
2. customa precipitation
3. concentrationThe reaction mixture was concentrated in vacuo
4. customto provide a brown solid which