Hydrochloric Acid → HCID 11645783, compound

Participants

Reaction Steps

Sodium 6-[N-(2,4difluorophenyl)sulfamoyl]-1-cyclohexene-1-carboxylate (0.48 g) was dissolved in water (100 ml) and adjusted at pH 1 to 2 with 1N HCl and then extracted with ethyl acetate (100 ml). The ethyl acetate layer was washed with water (100 ml×2) and dried over anhydrous magnesium sulfate and then the solvent was distilled off under reduced pressure. The residue was crystallized from diisopropyl ether to obtain 6-[N-(2,4-difluorophenyl)sulfamoyl]-1-cyclohexene-1-carboxylic acid (0.44 g) as white powdery crystals.

Provenance & Evidence