HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 22568991, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Cyclopropyl-ethyl-(2-methyl-4-trimethylsilanylethynyl-benzyl)-amine | HCID 22568965 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22568991 | HCID 22568991 | — |
Reaction Steps
Using General Procedure E; cyclopropyl-ethyl-(2-methyl-4-trimethylsilanylethynyl-benzyl)-amine (Intermediate 160, 650.0 mg, 2.30 mmols) in methanol (10 mL) was treated with potassium carbonate (100.0 mg, 0.72 mmol) and stirred overnight at ambient temperature. The crude alkyne (495 mg, 99%) was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495552B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-f780108f62f045518a3540b412cd1c46 |
| Source note | uspto-grants-2002_12 |