HuagongsheHuagongshe Chemistry Print Report · For research reference only
Leucine methyl ester hydrochloride → HCID 15484847, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Leucine methyl ester hydrochloride | HCID 2723695 | — |
| Reactant | 2-(3,4-Dichloro-phenylamino)-propionic Acid | HCID 6916426 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 15484847 | HCID 15484847 | — |
Reaction Steps
Following General Procedure D and using L-leucine methyl ester hydrochloride (Sigma) and N-(3,4-dichlorophenyl)-D,L-alanine (from Example A above), the title compound was prepared as a solid (mp=120-132° C.). The reaction was monitored by tlc (Rf=0.49 in 1:1 EtOAc:Hexanes) and the product was purified by flash chromatography using 1:1 EtOAc:Hexanes as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495693B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-c6e38a7742d64e658b81a0e7e9b5af2d |
| Source note | uspto-grants-2002_12 |