Methanol → Methyl (benzylthio)acetate

HRID 2299604Notes

Reaction equation

HRID 2299604 reaction equation
[CH2:1]([S:8][CH2:9][C:10]([OH:12])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:13]O>>[CH2:1]([S:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 887MethanolHCID 668972-((Phenylmethyl)thio)acetic acid

Product 1

HCID 562502Methyl (benzylthio)acetate

Procedure

S-benzylthioglycolic acid (12.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 20 minutes. The solvent was then removed under vacuum. Methyl S-benzylthioglycolate obtained was used in the next step without further purification.

Workup

  1. customsparged with hydrogen chloride gas at room temperature for 20 minutes
  2. customThe solvent was then removed under vacuum

Sources & evidence

ORD record
ord-468fb890d64e40a2a3924c8de2e5beb2
Source dataset
uspto-grants-2002_12
Patent number
US06495719B2

Reaction notes

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