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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2299630Generated: November 1, 2026

Ammonium Hydroxide → (2S)-(-)-1-Amino-3-phenoxy-2-propanol

https://huagongshe.com/reaction/2299630

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium HydroxideHCID 14923—
Reactant(2S)-2-(phenoxymethyl)oxiraneHCID 1534345—
SolventEthanolHCID 702—
Product(2S)-(-)-1-Amino-3-phenoxy-2-propanolHCID 1133101—

Reaction Steps

A stirred solution of (2S)-1-phenoxy-2,3-epoxypropane (1.0 g) and concentrated ammonium hydroxide (10 ml) in ethanol (10 ml) was sealed up at room temperature for 12 hours. The mixture was evaporated in vacuo and dried to give (2S)-1-amino-3-phenoxy-2-propanol (1.1 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06495546B1
Source datasetuspto-grants-2002_12
ORD IDord-8d90f494aca748ca814d7b380f61ec3b
Source noteuspto-grants-2002_12