反应详情

Heated was a mixture of urea 5.84 g (9.72 mmol) and benzylamine 25.0 g (23.3 mmol, 2.4 equivalents) at 150° C.-155° C. for 5 hours attaching with an air cooler. During the heating, observed was the ammonia gas evolution from colorless liquid reaction mixture. By cooling, it turned solidified at around room temperature. Purified was the reaction product by recrystallization from ethanol-benzene (1:1 mixture) to give N,N′-dibenzylurea 14.0 g as white fine needles (59.9% yield).

1. temperatureHeated
2. customfrom colorless liquid reaction mixture
3. temperatureBy cooling
4. customturned solidified at around room temperature
5. customPurified
6. customby recrystallization from ethanol-benzene (1:1 mixture)