Hydrazine hydrate (1:1) → HCID 54231997, compound

HRID 2300151Notes

Reaction equation

HRID 2300151 reaction equation
O.[NH2:2][NH2:3].[N:4]1([C:9]2[CH:10]=[C:11]([C:19]([O:21]C)=O)[C:12](=[CH:17][CH:18]=2)[C:13](OC)=[O:14])[CH:8]=[CH:7][CH:6]=[N:5]1>C(O)C>[N:4]1([C:9]2[CH:10]=[C:11]3[C:12](=[CH:17][CH:18]=2)[C:13](=[O:14])[N:3]=[N:2][C:19]3=[O:21])[CH:8]=[CH:7][CH:6]=[N:5]1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 22744587dimethyl 4-(1H-1-pyrazolyl)phthalate

Product 1

HCID 54231997HCID 54231997, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

22 ml hydrazine monohydrate was added to a mixture of 77 g dimethyl 4-(1H-1-pyrazolyl)phthalate and 500 ml ethanol, and heated under reflux for 6 hr. After cooling, the resulting precipitates were collected by filtration to give 36 g of 6-(1H-1-pyrazolyl)-1,4-phthalazine dione.

Workup

  1. temperatureheated
  2. temperatureunder reflux for 6 hr
  3. temperatureAfter cooling
  4. customthe resulting precipitates
  5. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-b409c0372048470ca24ec2282059e000
Source dataset
uspto-grants-2002_12
Patent number
US06498159B1

Reaction notes

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