HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl Acetate → 3-Oxo-2-oxa-8-azaspiro[4.5]decane hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl Acetate | HCID 8857 | — |
| Edukt | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Edukt | Tert-butyl 3-oxo-2-oxa-8-azaspiro[4.5]decane-8-carboxylate | HCID 22744536 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 3-Oxo-2-oxa-8-azaspiro[4.5]decane hydrochloride | HCID 21955313 | — |
Reaktionsschritte
1.16 g of tert-butyl 3-oxo-2-oxa-8-azaspiro[4.5]decane-8-carboxylate was dissolved in 2.3 ml methanol, 4.6 ml of 4 N hydrochloric acid/ethyl acetate was added thereto, and the mixture was stirred at room temperature for 1 hr. 5 ml ethyl acetate was added thereto, and the resulting crystals were collected by filtration to give 700 mg of 3-oxo-2-oxa-8-azaspiro[4.5]decane hydrochloride.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06498159B1 |
| Quelldatensatz | uspto-grants-2002_12 |
| ORD ID | ord-cad4471fb43a4d35819c7e2e545c791b |
| Quellennotiz | uspto-grants-2002_12 |