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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 23005Generated: October 25, 2026

3,5-Difluorophenylacetonitrile → 2-(3,5-Difluorophenylmethyl)-4-carboxy-2-thiazoline

https://huagongshe.com/reaction/23005

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DifluorophenylacetonitrileHCID 518565—
ReactantEthyl cysteinate hydrochlorideHCID 2723617—
Product2-(3,5-Difluorophenylmethyl)-4-carboxy-2-thiazolineHCID 22592487—

Reaction Steps

Following General Procedure G and using 3,5-difluorophenylacetonitrile and L-cysteine ethyl ester hydrochloride (Aldrich), the title compound was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06849650B2
Source datasetuspto-grants-2005_02
ORD IDord-1aeed726105c4d6481478fa43013ccdb
Source noteuspto-grants-2005_02