HCID 18374567, compound → HCID 12109773, compound

Participants

Reaction Steps

Preparation analogous to example II, starting from 83 mg of 4-(4-aminomethylphenyl)-1-(4-fluorophenyl)-3-(3-hydroxy-3-phenylpropyl)azetidin-2-one and 130 mg of [2-(2-{[3-(3-butyl-7-dimethylamino-3-ethyl-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1H-benzo[b]thiepin-5-yl)phenylcarbamoyl]methoxy}ethoxy)ethoxy]acetic acid; chromatography: SiO2, dichloromethane/methanol=20:1; product of melting point 120° C. and molecular weight 1021.3 (C57H67FN4O10S); MS (ESI+): 1021 (M+H+).

Provenance & Evidence