Cumylamine → HCID 17905808, compound

HRID 2300726Notes

Reaction equation

HRID 2300726 reaction equation
CS([C:5]1[N:10]=[C:9]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]=[CH:12]2)[CH:8]=[CH:7][N:6]=1)(=O)=O.[C:20]([NH2:29])([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)([CH3:22])[CH3:21]>>[C:23]1([C:20]([NH:29][C:5]2[N:10]=[C:9]([N:11]3[C:15]4[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=4[N:13]=[CH:12]3)[CH:8]=[CH:7][N:6]=2)([CH3:22])[CH3:21])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 68509CumylamineHCID 155496402-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine

Product 1

HCID 17905808HCID 17905808, compound

Procedure

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with cumylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 330.1 (M+1). 1H NMR (500 MHz, CDCl3): δ partial 8.37 (d, J=4.8 Hz, 1H); 8.05 (br s, 1H); 7.77 (d, J=7.6 Hz; 1H); 7.54 (d, J=7.8 Hz, 2H); 7.41 (m, 2H); 6.75 (d, J=5.5 Hz; 1H); 5.91 (br s, 1H); 1.81 (s, 6H).

Sources & evidence

ORD record
ord-d9aaf86dc7f64f17b14e056aeb5075b4
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

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