Furfurylamine → HCID 18375667, compound

HRID 2300736Notes

Reaction equation

HRID 2300736 reaction equation
CS([C:5]1[N:10]=[C:9]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]=[CH:12]2)[CH:8]=[CH:7][N:6]=1)(=O)=O.[CH2:20]([NH2:26])[C:21]1[O:25][CH:24]=[CH:23][CH:22]=1>>[O:25]1[CH:24]=[CH:23][CH:22]=[C:21]1[CH2:20][NH:26][C:5]1[N:10]=[C:9]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]=[CH:12]2)[CH:8]=[CH:7][N:6]=1

Participants

3

Reactant 2

HCID 3438FurfurylamineHCID 155496402-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine

Product 1

HCID 18375667HCID 18375667, compound

Procedure

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with furfurylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 292.1 (M+1). 1H NMR (500 MHz, CDCl3): δ 8.64 (s, 1H); 8.45 (s, 1H); 8.18 (m, 1H); 7.87 (m, 1H); 7.40 (m, 4H); 6.86 (d, J=5.5 Hz, 1H); 6.35 (m, 1H); 5.71 (br s, 1H); 4.75 (d, J=5.0 Hz, 2H).

Sources & evidence

ORD record
ord-eb58fd3ccc5041b7af1abe9e02401a5a
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

Loading…