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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300737Generated: October 31, 2026

4-Fluorobenzylamine → HCID 18375885, compound

https://huagongshe.com/reaction/2300737

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzylamineHCID 67326—
Reactant2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidineHCID 15549640—
ProductHCID 18375885HCID 18375885—

Reaction Steps

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with 4-fluorobenzylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 320.1 (M+1). 1H NMR (500 MHz, CDCl3): δ 8.60 (s, 1H); 8.43 (br s, 1H); 8.07 (br s, 1H); 7.86 (m, 1H); 7.38 (m, 5H); 7.07 (t, J=8.7 Hz, 1H); 6.85 (d, J=5.5 Hz, 1H); 5.79 (br s, 1H); 4.72 (d, J=5.7 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498165B1
Source datasetuspto-grants-2002_12
ORD IDord-0ad0d87eb658498aada1abdc82e388fb
Source noteuspto-grants-2002_12