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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300741Generated: October 31, 2026

2-Fluorobenzylamine → HCID 18375438, compound

https://huagongshe.com/reaction/2300741

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorobenzylamineHCID 66649—
Reactant2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidineHCID 15549640—
ProductHCID 18375438HCID 18375438—

Reaction Steps

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with 2-fluorobenzylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 320.1 (M+1). 1H NMR (500 MHz, CDCl3): δ partial 8.62 (s, 1H); 8.43 (br s, 1H); 8.09 (br s, 1H); 7.86 (m, 1H); 7.13 (m, 2H); 6.85 (d, J=5.3 Hz, 1H; 5.87 (br s, 1H); 4.81 (d, J=6.1 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498165B1
Source datasetuspto-grants-2002_12
ORD IDord-22e57a01211c49d7b49e506f67030ac1
Source noteuspto-grants-2002_12