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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300749Generated: October 28, 2026

3,5-Difluorobenzylamine → HCID 18375442, compound

https://huagongshe.com/reaction/2300749

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DifluorobenzylamineHCID 145211—
Reactant2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidineHCID 15549640—
ProductHCID 18375442HCID 18375442—

Reaction Steps

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with 3,5-difluorobenzylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 338.1 (M+1). 1H NMR (500 MHz, CDCl3): δ 8.58 (s, 1H); 8.45 (d, J=5.5 Hz, 1H); 7.98 (br s, 1H); 7.85 (d, J=8.5 Hz, 1H); 7.36 (m, 2H); 6.95 (d, J=6.4 Hz, 2H); 6.89 (d, J=5.4 Hz, 1H); 6.74 (m, 1H); 5.87 (br s, 1H); 4.75 (d, J=6.4 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498165B1
Source datasetuspto-grants-2002_12
ORD IDord-7ba2e8b822424653941660c5ed6698c9
Source noteuspto-grants-2002_12