HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 59924679, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- | HCID 66325 | — |
| Reactant | 2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine | HCID 15549640 | — |
| Product | HCID 59924679 | HCID 59924679 | — |
Reaction Steps
2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with (S)-1-(1-naphthyl)ethylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 366.1 (M+1). 1H NMR (500 MHz, CDCl3): δ partial 8.40 (d, J=4.6 Hz, 1H); 8.34 (br s, 1H); 8.23 (d, J=8.2 Hz, 1H); 7.97 (d, J=7.6 Hz, 1H); 7.82 (d, J=8.2 Hz, 1H); 7.67 (d, J=6.9 Hz, 1H); 7.47 (t, J=7.7 Hz, 1H); 6.77 (s, 1H); 6.03 (br s, 2H); 1.80 (d, J=6.7 Hz, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06498165B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-ba4d21ae1f824754867220eca35113a4 |
| Source note | uspto-grants-2002_12 |