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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300755Generated: November 2, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 59924679, compound

https://huagongshe.com/reaction/2300755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidineHCID 15549640—
ProductHCID 59924679HCID 59924679—

Reaction Steps

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with (S)-1-(1-naphthyl)ethylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 366.1 (M+1). 1H NMR (500 MHz, CDCl3): δ partial 8.40 (d, J=4.6 Hz, 1H); 8.34 (br s, 1H); 8.23 (d, J=8.2 Hz, 1H); 7.97 (d, J=7.6 Hz, 1H); 7.82 (d, J=8.2 Hz, 1H); 7.67 (d, J=6.9 Hz, 1H); 7.47 (t, J=7.7 Hz, 1H); 6.77 (s, 1H); 6.03 (br s, 2H); 1.80 (d, J=6.7 Hz, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498165B1
Source datasetuspto-grants-2002_12
ORD IDord-ba4d21ae1f824754867220eca35113a4
Source noteuspto-grants-2002_12