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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300756Generated: November 1, 2026

(1S)-1-phenylpropan-1-amine → HCID 59924874, compound

https://huagongshe.com/reaction/2300756

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S)-1-phenylpropan-1-amineHCID 6993773—
Reactant2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidineHCID 15549640—
ProductHCID 59924874HCID 59924874—

Reaction Steps

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with (S)-1-phenylpropylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 330.3 (M+1). 1H NMR (500 MHz, CDCl3): δ partial 8.49 (br s, 1H); 8.38 (d, J=5.5 Hz, 1H); 7.83 (d, J=7.6 Hz, 1H); 7.27-7.44 (m, 6H); 6.77 (d, J=5.5 Hz, 1H); 5.88 (br s, 1H); 4.97 (br s, 1H); 1.97 (m, 2H); 1.03 (t, J=7.5 Hz, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498165B1
Source datasetuspto-grants-2002_12
ORD IDord-32b1f7edf8c44ea0ad8b759599b73dd5
Source noteuspto-grants-2002_12