反应详情

To 8.0 g (0.03 mole) of 2[(2,6-dichlorophenyl)methylsulfinyl]-3-methyl-pyridine-N-oxide (See Example 29 above) in 150 ml of chloroform were added 10 g (0.05 mole) of metachloroperbenzoic acid. The mixture was stirred at room temperature for 24 hours, and then was washed with 20% K2CO3, and then with aqueous NaHSO3 until no peroxides were present. The chloroform layer was dried with Na2SO4 and then the mixture was filtered and the solvent removed on a steam bath. The residue was taken up in ether and filtered to give 2 g of solid, having a melting point of 215-218° C. The elemental analysis for C,H,N; the infrared, and the NMR all supported the proposed structure.

1. washwas washed with 20% K2CO3
2. dry with materialThe chloroform layer was dried with Na2SO4
3. filtrationthe mixture was filtered
4. customthe solvent removed on a steam bath
5. filtrationfiltered