Hydrochloric Acid → HCID 18377355, compound

Participants

Reaction Steps

A 1 ml portion of 5 N hydrochloric acid was added to acetic acid solution (10 ml) containing 0.52 g (1.70 mmol) of 3-t-butoxycarbonyl-1,2,3,4,4a,5-hexahydropyrazino[2,1-c]-1,4-benzthiazine, and the mixture was stirred overnight at room temperature and then at 60° C. for 2 hours. The solvent was removed by evaporation under a reduced pressure and the resulting residue was recrystallized from ethanol to obtain 0.36 g (88% in yield) of the title compound.

Provenance & Evidence