5-t-Butoxycarbonyl-2-methyl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine → HCID 18377285, compound

HRID 2301121Notes

Reaction equation

HRID 2301121 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]2[S:14][C:15]([CH3:17])=[CH:16][C:10]=2[CH2:9]1)=O)(C)(C)C>CO.Cl>[CH3:17][C:15]1[S:14][C:11]2[CH2:12][CH2:13][NH:8][CH2:9][C:10]=2[CH:16]=1

Participants

3

Reactant 1

HCID 183773565-t-Butoxycarbonyl-2-methyl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine

Product 1

HCID 18377285HCID 18377285, compound

Reagents, catalysts & solvents 1

HCID 21893726Hydrochloride methanolSolvent

Procedure

5-t-Butoxycarbonyl-2-methyl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine (100 mg, 0.40 mmol) was dissolved in hydrochloric acid methanol solution and stirred at room temperature for 14 hours. By evaporating the solvent from the reaction solution under a reduced pressure, 60 mg (0.39 mmol, 99% in yield) of the title compound was obtained.

Workup

  1. customBy evaporating the solvent from the reaction solution

Sources & evidence

ORD record
ord-82b6666a51ef471583929e28647909ce
Source dataset
uspto-grants-2002_12
Patent number
US06498251B1

Reaction notes

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