1-Methylpyrrolidine → HCID 16710845, compound

Participants

Reaction Steps

Colorless 1-methylpyrrolidine, 212 g (2.5 mol), was added dropwise to 144 g (2 mol) of trimethylaluminum at room temperature under nitrogen gas flow with stirring. After the addition of 1-methylpyrrolidine was completed, the resulting mixture was stirred for 6 hours at room temperature to complete the reaction. 1-Methylpyrrolidine trimethylaluminum was obtained after completion of the reaction and was dried under vacuum at about 45° C. to give 300 g of a colorless liquid. The dried colorless liquid was distilled under vacuum (10−2 torr) at 600° C., during which a colorless distillate was condensed inside a vessel cooled with dry ice. This first colorless distillate was purified according to the same procedure at 60° C. to give 267 g of the colorless and highly purified 1-methylpyrrolidine trimethylaluminum.

Provenance & Evidence