1-Methylpyrrolidine → HCID 16710845, compound

Colorless 1-methylpyrrolidine, 212 g (2.5 mol), was added dropwise to 144 g (2 mol) of trimethylaluminum at room temperature under nitrogen gas flow with stirring. After the addition of 1-methylpyrrolidine was completed, the resulting mixture was stirred for 6 hours at room temperature to complete the reaction. 1-Methylpyrrolidine trimethylaluminum was obtained after completion of the reaction and was dried under vacuum at about 45° C. to give 300 g of a colorless liquid. The dried colorless liquid was distilled under vacuum (10−2 torr) at 600° C., during which a colorless distillate was condensed inside a vessel cooled with dry ice. This first colorless distillate was purified according to the same procedure at 60° C. to give 267 g of the colorless and highly purified 1-methylpyrrolidine trimethylaluminum.

1. stirringthe resulting mixture was stirred for 6 hours at room temperature
2. customthe reaction

ORD record

ord-b2f81f9806f145eaa0f9f9ed82ae567d

Source dataset

uspto-grants-2002_12

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US06500250B1