Benzene, 1-ethoxy-4-isocyanato- → HCID 9889519, compound

HRID 2301271Notes

Reaction equation

HRID 2301271 reaction equation
[CH3:1][N:2]([CH3:17])[CH2:3][CH2:4][NH:5][C:6]1[S:7][C:8]([S:12]([NH:15][CH3:16])(=[O:14])=[O:13])=[C:9]([CH3:11])[N:10]=1.[CH2:18]([O:20][C:21]1[CH:26]=[CH:25][C:24]([N:27]=[C:28]=[O:29])=[CH:23][CH:22]=1)[CH3:19]>O1CCOCC1>[CH3:17][N:2]([CH3:1])[CH2:3][CH2:4][N:5]([C:28]([NH:27][C:24]1[CH:25]=[CH:26][C:21]([O:20][CH2:18][CH3:19])=[CH:22][CH:23]=1)=[O:29])[C:6]1[S:7][C:8]([S:12]([NH:15][CH3:16])(=[O:14])=[O:13])=[C:9]([CH3:11])[N:10]=1

Participants

4

Reactant 2

HCID 122887Benzene, 1-ethoxy-4-isocyanato-HCID 11357928HCID 11357928, compound

Product 1

HCID 9889519HCID 9889519, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1.0 g (3.59 mmol) of 2-{[2-dimethylaminoethyl]amino}-N,4-dimethyl-1,3-thiazole-5-sulphonamide and 586 mg (3.59 mmol) of 4-ethoxyphenyl isocyanate are dissolved in 30 ml of dioxane and stirred at room temperature for 12 h. The mixture is then concentrated in vacuo, and the residue is recrystallized from 2-propanol.

Workup

  1. concentrationThe mixture is then concentrated in vacuo
  2. customthe residue is recrystallized from 2-propanol

Sources & evidence

ORD record
ord-6c6e235a7851477ba1ee63fd8d627343
Source dataset
uspto-grants-2002_12
Patent number
US06500817B1

Reaction notes

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