HCID 18005470, compound → HCID 18005457, compound

HRID 2301385Notes

Reaction equation

HRID 2301385 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[C:12]([Br:13])=[CH:11][C:10]([C:14]([F:17])([F:16])[F:15])=[CH:9][C:8]=2[Br:18])[N:5]=[C:4]([C:19]#[N:20])[C:3]=1[S:21][C:22]#N>ICC.CO>[NH2:1][C:2]1[N:6]([C:7]2[C:8]([Br:18])=[CH:9][C:10]([C:14]([F:17])([F:15])[F:16])=[CH:11][C:12]=2[Br:13])[N:5]=[C:4]([C:19]#[N:20])[C:3]=1[S:21][CH3:22]

Participants

4

Reactant 1

HCID 18005470HCID 18005470, compound

Product 1

HCID 18005457HCID 18005457, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6340IodoethaneSolvent

Procedure

5-amino-1-[2,6-dibromo4-(trifluoromethyl)phenyl]-4-thiocyanato-1H-pyrazole-3-carbonitrile, which was used directly in step 2 with iodoethane and methanol as solvent to give the 5-amino-1-[2,6-dibromo-4-(trifluoromethyl)phenyl]-4-methylthio-1H-pyrazole-3-carbonitrile, m.p.211-214° C.

Sources & evidence

ORD record
ord-0bd436b3777740f8952e905a41ef0734
Source dataset
uspto-grants-2002_12
Patent number
US06500850B2

Reaction notes

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